abstract：:We report on a de novo interstitial deletion of (6)(q15q22.2) in a 5-year-old boy with developmental delay, microcephaly, facial dysmorphism, cryptorchidism, congenital heart defect, and split-hand malformation. Previous reports and this patient suggest that 6q21 may contain a gene or genes related either directly or ...

journal_title：Journal of applied genetics

authors： Duran-Gonzalez J,Gutierrez-Angulo M,Garcia-Cruz D,Ayala Mde L,Padilla M,Davalos IP

更新日期：2007-01-01 00:00:00

abstract：:In order to evaluate the phenotypic effects of implanted neural stem cells (NSCs) in the mouse model of Niemann-Pick C (NPC) disease, we injected a well-characterized clone of murine NSCs into the cerebella of neonatal Npc1(-/-) and control mice. The implanted cells survived and were abundant in some regions of the ce...

journal_title：Journal of applied genetics

authors： Ahmad I,Hunter RE,Flax JD,Snyder EY,Erickson RP

更新日期：2007-01-01 00:00:00

abstract：:Winter wheat cultivars Aquileja (AQ) and Xian Nong 4(XN) were previously reported to possess durable, quantitative resistance to stripe rust disease. In the present study, AQ, XN and a susceptible wheat cultivar were reciprocally crossed in all 6 combinations. Parents, F1, F2, F3, BCP1 and BCP2 were used to determine ...

journal_title：Journal of applied genetics

authors： Feng J,Zhang Z,Li G,Zhou Y,Wang H,Guo Q,Sun J

更新日期：2007-01-01 00:00:00

abstract：:In this work, a seed-set-based screening was performed on 70 lines of Arabidopsis thaliana after activation tagging mutagenesis to identify mutations in reproductive mechanisms. Five mutants showed significantly lower seed set than the wild type and confirmed the phenotype in the progeny. This phenotype was linked wit...

journal_title：Journal of applied genetics

authors： Perrella G,Cremona G,Consiglio F,Errico A,Bressan RA,Conicella C

更新日期：2006-01-01 00:00:00

abstract：:This study aimed to determine the frequency of associated urological abnormalities in children with unilateral renal agenesis (RA) or multicystic dysplastic kidney (MCDK). In total, 38 children (10 girls, 28 boys) were studied: 21 with RA and 17 with MCDK. In 14 children (37%) anomalies of the urinary tract were suspe...

journal_title：Journal of applied genetics

authors： Krzemień G,Roszkowska-Blaim M,Kostro I,Wojnar J,Karpińska M,Sekowska R

更新日期：2006-01-01 00:00:00

abstract：:Fast and efficient DNA fingerprinting of crop cultivars and individuals is frequently used in both theoretical population genetics and in practical breeding. Numerous DNA marker technologies exist and the ratio of speed, cost and accuracy are of importance. Therefore even in species where highly accurate and polymorph...

journal_title：Journal of applied genetics

authors： Smýkal P

更新日期：2006-01-01 00:00:00

abstract：:Myogenic factor 5 (myf-5) is the product of the MYF5 gene, belonging to the MyoD family. This transcription factor participates in the control of myogenesis. We identified 3 new mutations in the promoter region of the gene: A65C, C580T and C613T. The aim of this study was to evaluate the influence of the A65C transver...

journal_title：Journal of applied genetics

authors： Urbański P,Flisikowski K,Starzyński RR,Kurył J,Kamyczek M

更新日期：2006-01-01 00:00:00

abstract：:In this study a wide range of genetic markers (12 microsatellites, 7 blood-group loci, 10 blood-protein loci) and mitochondrial DNA (mtDNA) were used to assess genetic diversity in Polish Heavy horses. Three random samples were sequenced for 421 bp of the mitochondrial D-loop region, but no clear phylogenetic patterns...

journal_title：Journal of applied genetics

authors： Iwańczyk E,Juras R,Cholewiński G,Cothran EG

更新日期：2006-01-01 00:00:00

abstract：:Genetic relationships among 20 elite wheat genotypes were studied using microsatellite markers and pedigree analysis. A total of 93 polymorphic bands were obtained with 25 microsatellite primer pairs. Coefficient of parentage (COP) values were calculated using parentage information at the expansion level of 5. The ped...

journal_title：Journal of applied genetics

authors： Sud S,Bains NS,Nanda GS

更新日期：2005-01-01 00:00:00

abstract：:Streptomycin-resistant mutants were isolated from mutagenised cotyledon explants of Capsicum praetermissum Heiser & Smith. The explants were mutagenised with N-ethyl-N-nitrosourea, which resulted in a high frequency of streptomycin-resistant mutants (18.0%) and a low frequency of chlorophyll-deficient (albino) mutants...

journal_title：Journal of applied genetics

authors： Venkataiah P,Christopher T,Subhash K

更新日期：2005-01-01 00:00:00

abstract：:Recent evidence indicates an important role of inflammation pathways, airways remodeling and epithelium activation in asthma genetics. In particular, transcriptome studies have detected differentially expressed genes involved in eosinophil apoptosis, the arginase pathway, response to allergens or interleukins, and to ...

journal_title：Journal of applied genetics

authors： Malerba G,Pignatti PF

更新日期：2005-01-01 00:00:00

abstract：:Tibetan semi-wild wheat (Triticum aestivum ssp. tibetanum Shao) is one of the Chinese endemic hexaploid wheat genetic resources, distributed only in the Qinghai-Xizang Plateau of China. It has special characters, such as a hulled glume and spike disarticulation. However, seed dormancy, another important character for ...

journal_title：Journal of applied genetics

authors： Lan XJ,Wei YM,Liu DC,Yan ZH,Zheng YL

更新日期：2005-01-01 00:00:00

abstract：:Arylamine N-acetyltransferase (NAT) genes were targeted for inhibition using short hairpin RNA (shRNA) using two different RNA polymerase III promoters. Constructs were developed for NAT1 and NAT2, the endogenous mouse genes, and for human NAT1. There were fetal and neonatal deaths with these constructs, perhaps due i...

journal_title：Journal of applied genetics

authors： Cao W,Hunter R,Strnatka D,McQueen CA,Erickson RP

更新日期：2005-01-01 00:00:00

abstract：:Pollen proteases were discovered over 100 years ago, whereas the enzymes from female tissues have been used since the Roman era in simple biotechnological processes. In the last decade a great progress has been made in studies on plant proteases, including those from the generative organs. This paper reviews reports p...

journal_title：Journal of applied genetics

authors： Radłowski M

更新日期：2005-01-01 00:00:00

abstract：:A total of 244 domestic pigeons (Columba livia var. domestica) were genotyped using the PCR-RFLP method. A 999 bp fragment of the MTCYB gene was amplified. The amplification products were digested with restriction enzymes. PCR-RFLP for MvaI restriction enzyme was observed. Frequencies of alleles were as follows: MTCYB...

journal_title：Journal of applied genetics

authors： Dybus A,Knapik K

更新日期：2005-01-01 00:00:00

abstract：:This article reviews and updates current information on the possible genetic basis for cutaneous lupus erythematosus. The aetiology of this condition remains unknown and is believed to be multifactorial, involving genetic, environmental and retroviral factors. A genetic predisposition is probably the greatest risk fac...

journal_title：Journal of applied genetics

authors： Osmola A,Namysł J,Jagodziński PP,Prokop J

更新日期：2004-01-01 00:00:00

abstract：:Observations of a specific rDNA locus behaviour during the cell cycle were made by fluorescent in situ hybridisation (FISH) in 12 Lupinus species. Due to the pattern of chromatin de-condensation in that locus, the number of relevant sites in interphase nuclei was twice as high as the number of signals on metaphase chr...

journal_title：Journal of applied genetics

authors： Naganowska B,Zielińska A

更新日期：2004-01-01 00:00:00

abstract：:A simplified AFLP method, based on methylation-sensitive Alw44I restriction endonuclease, has been developed and evaluated for fingerprinting 15 wheat cultivars. The selected germplasms represented groups of spring and winter wheats with and without the 1BL.1RS translocation. Ten selective primers yielded 57 markers, ...

journal_title：Journal of applied genetics

authors： Tyrka M

更新日期：2004-01-01 00:00:00

abstract：:Psoriasis is a common skin disease with a genetic background and significant human leukocyte antigen (HLA) associations. HLA-Cw6 is the most frequently described association, particularly with psoriasis of the early onset type. Few studies of its correlation with various psoriasis clinical phenotypes and severity of t...

journal_title：Journal of applied genetics

authors： Szczerkowska-Dobosz A,Rebała K,Szczerkowska Z,Witkowska-Toboła A

更新日期：2004-01-01 00:00:00

abstract：:A linkage map of garden pea was constructed on the basis of 114 plants (F2 generation) derived from a cross combination Wt10245 x Wt11238. The map, consisting of 204 morphological, isozyme, AFLP, ISSR, STS, CAPS and RAPD markers, was used for interval mapping of quantitative trait loci (QTLs) controlling seed number, ...

journal_title：Journal of applied genetics

authors： Irzykowska L,Wolko B

更新日期：2004-01-01 00:00:00

abstract：:A moderate genotoxic activity of halothane and isoflurane applied as volatile anaesthetics has already been shown. The aim of this work was to estimate a potential genotoxicity of sevoflurane, introduced to clinical practice later than halothane and isoflurane. A genotoxic activity of all three compounds was estimated...

journal_title：Journal of applied genetics

authors： Szyfter K,Szulc R,Mikstacki A,Stachecki I,Rydzanicz M,Jałoszyński P

更新日期：2004-01-01 00:00:00

abstract：:The insulin-like growth factor 2 gene (IGF2) has been described in several studies as a candidate gene for meat efficiency in pigs. IGF2 is a member of the growth factors family and has an effect on development of muscle tissue. The effect of IGF2 gene polymorphism on meat efficiency was analysed in a population of 12...

journal_title：Journal of applied genetics

authors： Kolaríková O,Putnová L,Urban T,Adámek J,Knoll A,Dvorák J

更新日期：2003-01-01 00:00:00

abstract：:Interspecific amphihaploid and amphidiploid hybrids between Nicotiana glauca Grah. (2n = 24) and N. tabacum L. (2n = 48) cultivars BY 103 and K 326 were analysed. F1 amphihaploids (2n = 36) were viable and completely self- and cross-sterile, and mostly univalents were present during meiosis (with pairing range from 0 ...

journal_title：Journal of applied genetics

authors： Trojak-Goluch A,Berbeć A

更新日期：2003-01-01 00:00:00

abstract：:Starting from two datasets of codon usage in coding sequences from mesophilic and thermophilic bacteria, we used internal correspondence analysis to study the variability of codon usage within and between species, and within and between amino acids. The first dataset included 18,958,458 codons from 58,482 coding seque...

journal_title：Journal of applied genetics

authors： Lobry JR,Chessel D

更新日期：2003-01-01 00:00:00

abstract：:Spring wheat nursery accessions, including 18 spring wheat lines derived in CIMMYT, Mexico, and 12 spring wheat cultivars bred in Poland, along with cultivars Frontana and Sumai 3 as resistant controls, were examined for resistance to leaf rust under field conditions. Multipathotype tests with 16 different pathogen is...

journal_title：Journal of applied genetics

authors： Wiśniewska H,Stepień Ł,Kowalczyk K

更新日期：2003-01-01 00:00:00

abstract：:Chromosome pairing in tetraploid Secalotriticum was analysed. In the studied plants wheat chromosomes in PMCs during metaphase I showed a higher degree of pairing, in comparison to the rye genome. This is reflected in a very low frequency of univalents and a higher frequency of ring bivalents. The occurrence of wheat ...

journal_title：Journal of applied genetics

authors： Apolinarska B

更新日期：2003-01-01 00:00:00

abstract：:The study aimed at development of a multiplex PCR system for amplification of three Y-chromosome STR loci: DYS390, DYS392 and DYS393, and its application in haplotype polymorphism analysis in the population of northern Poland. Due to interactions between originally published primers, a new DYS392 primer pair was propo...

journal_title：Journal of applied genetics

authors： Rebała K,Kapińska E,Szczerkowska Z

更新日期：2003-01-01 00:00:00

abstract：:The simplified AFLP method was developed and evaluated for identification and genetic diversity studies of wheat cultivars. Selective primers exploited in AFLP assay based on a single cutting enzyme PstI ((PstI)AFLP) generated total of 111 robust fragments, including 67 (60%) monomorphic and 12 (11%) cultivar-specific...

journal_title：Journal of applied genetics

authors： Tyrka M

更新日期：2002-01-01 00:00:00

abstract：:The long QT syndrome (LQTS) is a disorder of ventricular repolarization that exposes affected individuals to cardiac arrhythmias and sudden death. The first gene for LQTS has been mapped to chromosome 11 p.15.5 by genome-wide linkage analysis. This gene, originally named KVLQT1 (and later KCNQ1), is a novel potassium ...

journal_title：Journal of applied genetics

authors： Moric E,Herbert E,Mazurek U,Samelska J,Cholewa K,Trusz-Gluza M,Wilczok T

更新日期：2002-01-01 00:00:00

abstract：:Selective DNA pooling is an advanced methodology for linkage mapping of quantitative trait loci (QTL) in farm animals. The principle is based on densitometric estimates of marker allele frequency in pooled DNA samples of phenotypically extreme individuals from half-sib, backcross and F(2) experimental designs in farm ...

journal_title：Journal of applied genetics

authors： Pareek CS,Pareek RS,Walawski K

更新日期：2002-01-01 00:00:00

abstract：:The aim of this study was to evaluate phenotypic variation of R0 androgenic plants obtained from four seed sources and donor plants by anther culture. Several morphological traits (leaf size, petiole length, leaf division, cortex colour) and the range of diversity were evaluated. There was large variation in all trait...

journal_title：Journal of applied genetics

authors： Kozik EU,Nowak R,Kłosińska U,Górecka K,Krzyzanowska D,Górecki R

更新日期：2002-01-01 00:00:00

abstract：:Hemp (Cannabis sativa L.) is a species considered as having one of the most complicated mechanisms of sex determination. Peroxidase and esterase isoenzymes in leaves of the two sexual phenotypes of hemp were studied. Significant differences in isoperoxidase and isoesterase patterns were found between male and female p...

journal_title：Journal of applied genetics

authors： Truţa E,Gille E,Tóth E,Maniu M

更新日期：2002-01-01 00:00:00

abstract：:SDS-PAGE analysis of seed globulins covered 200 accessions of the following Lens taxa: L. culinaris subsp. culinaris, L. culinaris subsp. orientalis, L. odemensis, L. ervoides, L. nigricans, L. lamottei and L. tomentosus. The number of polypeptide bands detected in particular taxa varied from 22 in L. lamottei to 35 i...

journal_title：Journal of applied genetics

authors： Zimniak-Przybylska Z,Przybylska J,Krajewski P

更新日期：2001-01-01 00:00:00

abstract：:The mode of replication and organisation of bacterial genomes impose asymmetry on their nucleotide composition. The asymmetry is seen in coding and non-coding sequences and is reflected in the amino acid composition of proteins. The mechanisms generating asymmetry include: unequal mutation rates connected with replica...

journal_title：Journal of applied genetics

authors： Kowalczuk M,Mackiewicz P,Mackiewicz D,Nowicka A,Dudkiewicz M,Dudek MR,Cebrat S

更新日期：2001-01-01 00:00:00

abstract：:Porcine pregnancy-associated glycoprotein genes (pPAG) are known as a multigene family, in which five members have been cloned and sequences of their cDNAs identified. Porcine PAG1 and pPAG3 genes, belonging to the pPAG1-like subfamily, both encode enzymatically inactive precursors. In contrast, cDNAs of pPAG2, pPAG4 ...

journal_title：Journal of applied genetics

authors： Szafrańska B,Panasiewicz G,Wacławik A

更新日期：2001-01-01 00:00:00

abstract：:Progress in mammalian cloning started from cloning embryos (of mice, rats, rabbits, sheep, goats, pigs, cattle and rhesus monkeys) and culminated in obtaining clones of sheep, cattle, pigs and mice from adult somatic cells. Knowing the relationship between the cell cycles of the recipient and the donor of cell nucleus...

journal_title：Journal of applied genetics

authors： Modliński JA,Grabarek J,Płusa B,Karasiewicz J

更新日期：2001-01-01 00:00:00

abstract：:Flow cytometry was used to screen ploidy levels in 47 cultured in vitro sugar beet gynogenetic lines of various origin and age, obtained after plant regeneration from unfertilized ovules. When donor plants were diploid, the majority of regenerants were found to have cells with 1C, 2C and 4C relative DNA content (mainl...

journal_title：Journal of applied genetics

authors： Svirshchevskaya A,Dolezel J

更新日期：2001-01-01 00:00:00

abstract：:The genetic determination of variability of barley doubled haploid (DH) lines in regard of their susceptibility to Fusarium head blight caused by Fusarium culmorum was studied. The susceptibility was evaluated in 3-year field experiment on the basis of reduction in yield traits and myotoxin accumulation in infected ke...

journal_title：Journal of applied genetics

authors： Surma M,Adamski T,Chełkowski J,Goliński P,Kaczmarek Z,Kostecki M,Perkowski J,Wiśniewska H

更新日期：2000-01-01 00:00:00